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Objectives: To evaluate the impact of COVID-19 pandemic on orthodontic treatment and mental health of patients undergoing orthodontic treatment and to compare their mental health with the age-matched control group. Materials and methods: 484 orthodontic patients (245 males and 239 females) and 200 age-matched control subjects were divided into two age groups. Group 1 had 14-18 years of adolescents (N = 274) and 100 control participants (Group 2) and Group 3 comprised of 19 years above adults (N = 210) and 100 control participants (Group 4). Group 1 and 3 patients filled the 4 sections of the questionnaire related to orthodontic emergencies (Sections 1-3) and mental distress (Kessler Psychological Distress Scale-Section 4), while groups 2 and 4 were asked to fill only Section-4. The comparison of mental distress on high/low Kessler scores was made using the Chi-Square test/Fisher's exact test. The factors which came out to be significant were put to bivariate logistic regression analysis. Results: The percentage of patients with high Kessler scores among Group 1 and Group 3 were 9.9% and 17.2% respectively, and their differences with age-matched control groups were non-significant. The mean differences of Kessler score were significantly higher for Group 3 compared to group 1. The higher Kessler score was associated with age, higher education, a feeling of concern for non-availability of appointments, increased treatment duration, its effect on the quality of treatment, and sabotaging of definitive future plans. Conclusions: The orthodontic treatment and emergencies may not be a significant factor contributing to increased stress among patients during the lockdown.
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Background: India intends to start its 1st dose of vaccination against Covid-19 on January 16th, 2021 prioritizing its frontline health care professionals with either of the two vaccines-Covaxin or Covishield. Whenever a new vaccine is launched, it is marred with controversy and myths. To understand the doubts and concerns better, this study was conducted on health care professionals working in a tertiary care hospital. Materials and Methods: Willing respondents, who are working in the institute, were administered the questionnaire asking their views on knowledge, beliefs, and reasons for hesitancy regarding Covid-19 immunization. A Likert scale was used to quantify the responses regarding participants' knowledge, beliefs, and hesitancies regarding immunization with the available vaccines. Data were analyzed using MS office Excel sheets and JASP software was used to analyze the data thus obtained. Results: Out of 122 complete responses, we had 73 (60%) doctors, while 30 (24%) were nursing staff, the rest comprised of other health care workers, such as housekeeping staff, janitorial, etc., 66 (54%) respondents were unaware, while 25 (20%) respondents had hesitancy and 23 (18%) were having extremely negative views regarding vaccination. Some of the variables, such as age, role, marital status, gender, etc., were found to be possibly associated with these scores. Conclusion: Issues like concerns over vaccine safety, efficacy, reliability, etc., are deterrents for individuals and whole programme and vaccination drive across the nation. Time and again it has been seen that despite the vaccines' contribution in breaking the transmission, concerns are making people either hesitant or unmotivated to get the vaccines. More dialogues from the authorities regarding the issues of concern may pave the way for more motivation to accept vaccination and increase the vaccination coverage.
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What is the future of the BRICS (Brazil–Russia–India–China–South Africa) group? BRICS has transformed in record time from a global non‐entity into an informal institution that pursues global policy leadership, features extensive policy coordination among five powerful countries, and creates its own organizations. While BRICS momentum seemed unstoppable, a militarized dispute between India and China in 2020 raised questions about the group’s future. This contribution concludes the Special Section by arguing that the BRICS group is not broken. Instead, it faces a range of strategic, geopolitical and operational challenges: how it addresses them will define its future trajectory and its impact on global governance. This essay analyses the situation from a conflict resolution perspective while bringing together insights from the five BRICS countries. It conceptualizes new directions for the BRICS group. Two possible internal conflict management scenarios are outlined: circumventing conflict and making institutional adjustments. Yet the real test of the group’s resilience is its ability to exert collective leadership and improve global governance. BRICS’ response to COVID‐19 and to the challenge of sustainable development offers insights into the group’s ability to advance community goals.
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The coronavirus disease 2019 (COVID-19) pandemic remains a source of considerable morbidity and mortality throughout the world. Therapeutic options to reduce symptoms, inflammatory response, or disease progression are limited. This randomized open-label trial enrolled 100 ambulatory patients with symptomatic COVID-19 in Toronto, Canada. Results indicate that icosapent ethyl (8 g daily for 3 days followed by 4 g daily for 11 days) significantly reduced high-sensitivity C-reactive protein (hs-CRP) and improved symptomatology compared with patients assigned to usual care. Specifically, the primary biomarker endpoint, change in hs-CRP, was significantly reduced by 25% among treated patients (-0.5 mg/L, interquartile range [IQR] [-6.9,0.4], within-group p = 0.011). Conversely, a non-significant 5.6% reduction was observed among usual care patients (-0.1 mg/L, IQR [-3.2,1.7], within-group p = 0.51). An unadjusted between-group primary biomarker analysis was non-significant (p = 0.082). Overall, this report provides evidence of an early anti-inflammatory effect of icosapent ethyl in a modest sample, including an initial well-tolerated loading dose, in symptomatic outpatients with COVID-19. ClinicalTrials.gov Identifier: NCT04412018.
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BACKGROUND: As the number of cases of COVID19 from novel corona virus 2019 rises so are the number of deaths ensuing from it. Doctors have been in front in these calamitous times across the world. India has less number of doctors so doctors are overwhelmed with more number of patients to cater. Thereby they are also fearing that they will be exposed much as they often work in limited resource settings. METHODS: An on line survey was to include doctors from eastern states in India for measuring the reasons of their fear and suggest possible solutions based on the results achieved thus. After IEC clearance a semi-structured anonymous questionnaire was sent on google forms as links on known to doctors, working in screening OPDs or flu clinics especially for COVID-19. RESULTS: Out of 59 Doctors majority were provided with sanitizers for practicing hand hygiene. Gloves were provided everywhere but masks particularly N95 and Triple Layer surgical masks were not there for all. Training was not given universally. Fear was dependent on age in our sample. CONCLUSION: Training and strict adherence to infection control measures along with resources can help in removing the fear.
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The world has declared COVID-19 (a disease caused by the SARS-CoV-2 virus or novel coronavirus) to be a pandemic. China has been chastised by various countries, especially the United States, for suppressing information and not taking necessary measures which could have helped in controlling the spread of and/or eradicating the disease in the earlier stages. Consequently, China has undertaken numerous measures to change the COVID-19 narrative and disassociate itself from COVID-19. It launched a campaign to question the origins of SARS-CoV-2, blamed the United States for spreading COVID-19, claimed victory in combating COVID-19 domestically, and provided aid (?mask diplomacy?) to countries. These actions betray China?s concern about its image. The country wants to portray itself as a Good Samaritan, a responsible and reliable partner, and an essential global power. Additionally, China has grave concerns about regime stability and survival. President Xi?s legitimacy is built on technocratic competence. The outbreak has the potential to seriously dent his personal legacy.